Quoting%20commentary for Ketubot 221:24

שלחו ליה אחוהי לרבה יודע היה יעקב שצדיק גמור היה וכו' אילפא מוסיף בה דברים מעשה באחד שהיה מצטער על אשה אחת וביקש לירד כיון ששמע כזאת גלגל בעצמו עד יום מותו

His brothers sent [the following message] to Rabbah: Jacob knew that he was a righteous man in every way etc. Ilfa added to this the following incident. It happened that a man was once troubled on account of [his inability to marry] a certain woman and desired to go down [to her country]; but as soon as he heard this he suffered until the day of his death.

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